KPV vial.png
KPV vial.png

KPV 10mg

$50.00
sold out

KPV is a tripeptide fragment derived from the C-terminal region of alpha-melanocyte-stimulating hormone (α-MSH), consisting of the amino acids lysine–proline–valine. It retains key anti-inflammatory properties of α-MSH while lacking melanogenic activity. KPV has been shown to modulate inflammatory signaling pathways, including inhibition of NF-κB activation and downstream pro-inflammatory cytokine production. Its small size contributes to stability and allows for targeted investigation in models of localized inflammation and immune response regulation.

Research applications include investigating cytokine modulation, particularly TNF-α, IL-1β, and IL-6, along with effects on NF-κB pathway signaling, epithelial barrier integrity, and macrophage-driven inflammatory responses.

Get notified by email when this product is in stock.

KPV is a tripeptide fragment derived from the C-terminal region of alpha-melanocyte-stimulating hormone (α-MSH), consisting of the amino acids lysine–proline–valine. It retains key anti-inflammatory properties of α-MSH while lacking melanogenic activity. KPV has been shown to modulate inflammatory signaling pathways, including inhibition of NF-κB activation and downstream pro-inflammatory cytokine production. Its small size contributes to stability and allows for targeted investigation in models of localized inflammation and immune response regulation.

Research applications include investigating cytokine modulation, particularly TNF-α, IL-1β, and IL-6, along with effects on NF-κB pathway signaling, epithelial barrier integrity, and macrophage-driven inflammatory responses.

Purity: >99%

Supplied as: Solid

Solubility: Water-soluble

Storage (lyophilized): stable at 4C for ≤ 2 years. Stable at -18C for ≤ 3 years.

*Note: lyophilized peptides can remain stable at room temperature for 30-60 days, but should be stored at 4C for optimum stability and longevity.

Storage (reconstituted): stable at 4C for ≤ 30 days. Long term storage in aqueous solution not recommended without sterile buffer at pH 5-6 and freezing to -80C.

WARNING: This product is NOT for human consumption or use in veterinary applications. Research use only.

Batch Specific Data
Laboratory Name Size Batch # Key Date Purity (%) Mass (mg)
Janoshik Analytical 10mg 63162 YQU6DR9QFRGS 04/27/25 99.591 12.02